SQL UNIQUE Constraint

The UNIQUE constraint ensures that all values in a column are different.
Both the UNIQUE and PRIMARY KEY constraints provide a guarantee for uniqueness for a column or set of columns.
A PRIMARY KEY constraint automatically has a UNIQUE constraint.
However, you can have many UNIQUE constraints per table, but only one PRIMARY KEY constraint per table.

SQL UNIQUE Constraint on CREATE TABLE

The following SQL creates a UNIQUE constraint on the "ID" column when the "Persons" table is created:
SQL Server / Oracle / MS Access:

CREATE TABLE Persons (
    ID int NOT NULL UNIQUE,
    LastName varchar(255) NOT NULL,
    FirstName varchar(255),
    Age int
);

MySQL:

CREATE TABLE Persons (
    ID int NOT NULL,
    LastName varchar(255) NOT NULL,
    FirstName varchar(255),
    Age int,
    UNIQUE (ID)
);

To name a UNIQUE constraint, and to define a UNIQUE constraint on multiple columns, use the following SQL syntax:
MySQL / SQL Server / Oracle / MS Access:

CREATE TABLE Persons (
    ID int NOT NULL,
    LastName varchar(255) NOT NULL,
    FirstName varchar(255),
    Age int,
    CONSTRAINT UC_Person UNIQUE (ID,LastName)
);